Thermo Fisher Scientific MCP-1 Polyclonal Antibody
Thermo Fisher Scientific의 MCP-1 Polyclonal Antibody는 마우스 CCL2/JE/MCP-1을 인식하는 고특이성 항체로, WB, ELISA, Neutralization에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 낮은 엔도톡신 수준과 높은 순도를 제공합니다.
- 카탈로그번호
- PA546954
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| ELISA (Detection) | 0.1–0.4 µg/mL |
| ELISA (Capture) | 0.2–0.8 µg/mL |
| Neutralization (Neu) | 0.5–2.5 µg/mL |
Publications
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse CCL2/JE/MCP-1 (Gln24–Arg96) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609536 |
Product Specific Information
- In sandwich ELISAs, less than 0.01% cross-reactivity is observed with recombinant human or mouse MCP family members and related chemokines.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
This gene encodes a cytokine located on chromosome 17q, part of a cytokine cluster involved in immunoregulatory and inflammatory processes. The encoded protein belongs to the CXC cytokine subfamily, characterized by two cysteines separated by one amino acid. MCP-1 shows chemotactic activity for monocytes and basophils, and is implicated in diseases with monocytic infiltration such as psoriasis, rheumatoid arthritis, and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-46954_CCL2_MCP-1_P10148-1_Goat.svg, PA5-46954_CCL2_MCP-1_P10148-1_Goat_PDP.jpeg)
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