Thermo Fisher Scientific CCL23 Polyclonal Antibody
Human CCL23 인식 Goat Polyclonal Antibody로 Western blot 및 Neutralization 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 순도를 제공. E. coli 유래 재조합 단백질을 면역원으로 사용하며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Neutralization (Neu) | 0.15–0.75 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human CCL23/Ck beta 8-1 Met46–Asn137 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608480 |
Product Specific Information
In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant human MPIF-1 is observed.
This antibody neutralizes the biological activity of human CCL23/Ck beta 8-1 and also neutralizes recombinant human MPIF-1 at a 10-fold higher Ig concentration.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endotoxin level is <0.20 EU per 1 µg of the antibody by the LAL method.
Target Information
The CCL23 gene is one of several chemokine genes clustered on the q-arm of chromosome 17.
Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.
This chemokine, a member of the CC subfamily, shows chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils, and no activity on activated T lymphocytes.
It acts as a strong suppressor of colony formation by multipotential hematopoietic progenitor cells and as a potent agonist of the chemokine (C-C motif) receptor 1.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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