Thermo Fisher Scientific LGMN Recombinant Rabbit Monoclonal Antibody (ARC1864)
Thermo Fisher Scientific의 LGMN Recombinant Rabbit Monoclonal Antibody (ARC1864)는 인간 및 생쥐에 반응하는 재조합 단일클론 항체로, Western blot 및 ELISA에 적합합니다. HEK293 세포에서 발현되었으며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1864 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 210–302 of human Legumain (LGMN) (Q99538) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898079 |
Product Specific Information
- Positive Samples: 293T, HepG2, MCF7, Mouse brain, Mouse spleen, Mouse kidney
- Immunogen sequence:
ANPRESSYAC YYDEKRSTYL GDWYSVNWME DSDVEDLTKE TLHKQYHLVK SHTNTSHVMQ YGNKTISTMK VMQFQGMKRK ASSPVPLPPV THL
Target Information
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. It may be involved in processing bacterial peptides and endogenous proteins for MHC class II presentation in lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells, and a mature active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression may be associated with many solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants exist, though only two have confirmed biological validity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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