Thermo Fisher Scientific ALOX5 Monoclonal Antibody (OTI2C7), TrueMAB

Applications

• Western Blot (WB): 1:2,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The ALOX5 gene encodes a protein essential for leukotriene synthesis in conjunction with the Arachidonate 5-lipoxygenase-activating protein. Leukotrienes are arachidonic acid metabolites involved in inflammatory responses such as asthma, arthritis, and psoriasis. The protein localizes to the plasma membrane. Inhibitors of its function block 5-lipoxygenase translocation from the cytoplasm to the membrane and inhibit its activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.