Thermo Fisher Scientific Human EPO (Erythropoietin) Recombinant Protein

Thermo Fisher Scientific Human EPO (Erythropoietin) Recombinant Protein

Applications

• Western Blot (WB): Assay-dependent
• Immunohistochemistry (IHC): Assay-dependent
• ELISA: Assay-dependent
• Functional Assay: Assay-dependent
• Control (Ctrl): Assay-dependent

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Product Specifications

Product Specific Information

Carrier-Free

• Reconstitution:
  Briefly centrifuge vial before opening to bring contents to bottom.
  Reconstitute in sterile, deionized water to 12,000–120,000 IU/mL.
  Further dilutions can be made in aqueous buffers.
  For long-term storage, supplement EPO solutions with 0.1% HSA or BSA.

• Storage:
  Lyophilized preparation is stable at room temperature for three weeks, but should be stored desiccated below -18°C.
  Upon reconstitution, stable for up to one week at 2–8°C; store below -18°C for long-term.
  Avoid repeated freeze/thaw cycles.

Target Information

Erythropoietin (EPO) is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. It induces final maturation of partially differentiated erythroid cells and promotes production of red cell-specific proteins such as hemoglobin.
EPO receptor (EPOR) is highly expressed on precursor cells and decreases with maturation.
In the fetus, hepatocytes are the main source of EPO; in adults, kidney interstitial cells predominate.
EPO expression increases during hypoxia, with low levels also found in lung and brain tissue.
Recent data suggest EPO may protect neuronal tissue and aid in repair processes.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.