Thermo Fisher Scientific Calreticulin (CALR) Monoclonal Antibody (OTI13E4)
Calreticulin(CALR)에 특이적인 단일클론 항체로 Western blot에 적합. 인간, 마우스, 랫트 반응성. 무보존제, 동결건조 형태로 제공되며 1 mg/mL 농도. 연구용으로 단백질 접힘 및 ER 품질관리 연구에 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI13E4 |
| Immunogen | Full length human recombinant protein of human CALR (NP_004334) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Calreticulin (Calr) is a calcium-binding chaperone that assists in protein folding, oligomeric assembly, and quality control within the endoplasmic reticulum (ER) through the calreticulin/calnexin cycle.
Calr transiently interacts with monoglucosylated glycoproteins synthesized in the ER and with the DNA-binding domain of NR3C1, mediating its nuclear export.
It may also play a role in maternal gene expression regulation and oocyte maturation by controlling calcium homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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