Thermo Fisher Scientific Calreticulin (CALR) Monoclonal Antibody (OTI13H4)
Calreticulin(CALR) 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. Human, Mouse, Rat 반응성. Lyophilized 형태, PBS+8% trehalose buffer. 연구용으로 사용되며, 재구성 및 결합 실험에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI13H4 |
| Immunogen | Full length human recombinant protein of human CALR (NP_004334) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Calreticulin (Calr) is a calcium-binding chaperone that assists in protein folding, oligomeric assembly, and quality control within the endoplasmic reticulum (ER) through the calreticulin/calnexin cycle.
It transiently interacts with monoglucosylated glycoproteins synthesized in the ER and with the DNA-binding domain of NR3C1 to mediate nuclear export.
Calr may also play a role in maternal gene expression regulation and oocyte maturation via calcium homeostasis.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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