Thermo Fisher Scientific CD56 Monoclonal Antibody (MEM-188), PE
CD56 (NCAM) 항원을 인식하는 MEM-188 클론의 PE 결합 단일클론 항체. 인간 및 비인간 영장류 반응성. 유세포분석에 적합하며, 565/576 nm 형광 특성. 액상 형태로 4°C 암소 보관, 동결 금지.
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Applications and Tested Dilution
Flow Cytometry (Flow)
- Tested Dilution: 20 µL/100 µL whole blood
- Publications: View 3 publications
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-188 |
| Immunogen | KG-1 human acute myelogenous leukaemia cell line |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073089 |
Available Formats
Product Specific Information
This antibody reacts with an extracellular epitope on a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
Target Information
CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120–180 kDa.
It is found on T cells and NK cells and is involved in cell migration, axonal growth, pathfinding, and synaptic plasticity.
CD56 is widely used as a neuroendocrine marker with high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors.
Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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