Thermo Fisher Scientific CD56 Monoclonal Antibody (MEM-188), PE

Applications and Tested Dilution

Flow Cytometry (Flow)

• Tested Dilution: 20 µL/100 µL whole blood
• Publications: View 3 publications

Miscellaneous PubMed (Misc)

• Publications: View 1 publication

Product Specifications

Available Formats

• Unconjugated
• APC
• Biotin
• FITC
• PerCP
• Request custom conjugation

Product Specific Information

This antibody reacts with an extracellular epitope on a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.

Target Information

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120–180 kDa.
It is found on T cells and NK cells and is involved in cell migration, axonal growth, pathfinding, and synaptic plasticity.
CD56 is widely used as a neuroendocrine marker with high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors.
Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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