Thermo Fisher Scientific S6 Recombinant Rabbit Monoclonal Antibody (9H8L2), Alexa Fluor 488
Alexa Fluor 488으로 표지된 재조합 토끼 단클론 항체로, 인간 RPS6 단백질(aa 2-249)에 특이적입니다. ICC/IF에 적합하며 우수한 특이성과 재현성을 제공합니다. 단백질 A로 정제된 액상 형태로, 4°C 암소 보관이 필요합니다.
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Applications
- Immunocytochemistry (ICC/IF): 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9H8L2 |
| Immunogen | Recombinant protein corresponding to amino acids 2–249 of human RPS6 |
| Conjugate | Alexa Fluor™ 488 |
| Excitation / Emission Max | 499 / 520 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2663047 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened for optimal production.
Advantages include:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
Ribosomes catalyze protein synthesis and consist of a small 40S and large 60S subunit, composed of RNA and ~80 proteins. The RPS6 gene encodes a cytoplasmic ribosomal protein of the 40S subunit, part of the S6E family.
RPS6 is a major substrate for ribosomal protein kinases, with C-terminal serine residues phosphorylated by various kinases. Phosphorylation is induced by growth factors and mitogens; dephosphorylation occurs during growth arrest.
This protein contributes to the regulation of cell growth and proliferation via selective mRNA translation. Multiple processed pseudogenes exist throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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