
Thermo Fisher Scientific RelB Recombinant Rabbit Monoclonal Antibody (24GB5070)
RelB 단백질을 표적으로 하는 재조합 토끼 단클론 항체로 Western blot 및 유세포분석에 적합. 인간, 생쥐, 랫트 반응성. HEK293F 발현 시스템 사용, 액상 형태, 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
- 카탈로그번호
- MA557685
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 24GB5070 |
| Immunogen | A synthesized peptide derived from human Rel B (aa 565–579) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Dry ice (international) |
Target Information
The NFκB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNA-binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a unique protein derived from the amino-terminus of a precursor designated p105. A second protein, designated p52 (previously referred to as p49), can act as an alternative NFκB subunit. Rel B does not bind with high affinity to NFκB sites, but heterodimers between Rel B and p50 bind with comparable affinity to p50 NFκB homodimers. However, Rel B/p50 heterodimers, in contrast to NFκB heterodimers, transactivate transcription of promoters containing κB binding sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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