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Thermo Fisher Scientific MUC18/CD146/MCAM (Melanoma Cell Adhesion Molecule) Monoclonal Antibody (OJ79c)
상품 한눈에 보기
인간 CD146(MCAM) 단백질을 인식하는 마우스 단클론 항체로, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 비접합형 액상 형태로 제공되며, 고순도 Protein A/G 정제 제품. 세포 접착 및 신호전달 연구에 적합.
- 카탈로그번호
- 4162-MSM1-P1ABX
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 04. 오후 04:54
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific 4162-MSM1-P1ABX MUC18/CD146/MCAM (Melanoma Cell Adhesion Molecule) Monoclonal Antibody (OJ79c) 100 ug pk판매 단위 pk ·
재고 확인 필요
900,300원VAT 포함 990,330원
Thermo Fisher Scientific · Thermo Fisher Scientific MUC18/CD146/MCAM (Melanoma Cell Adhesion Molecule) Monoclonal Antibody (OJ79c)
Thermo Fisher Scientific MUC18/CD146/MCAM (Melanoma Cell Adhesion Molecule) Monoclonal Antibody (OJ79c)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OJ79c |
| Immunogen | Recombinant full-length human MUC18 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed at cell-cell junctions in all endothelial cells and in various normal and malignant cell types. CD146 functions as a calcium-independent cell adhesion molecule and may also act as a signal transduction molecule by recruiting Fyn kinase, leading to tyrosine phosphorylation of proteins involved in actin cytoskeleton assembly.
CD146 plays a key role in:
- Cell adhesion and endothelial monolayer cohesion
- Interaction of melanoma cells with vascular elements, promoting tumor spread
- Neural crest cell adhesion during embryonic development
- Surface receptor activity triggering phosphorylation of FYN and PTK2 and transient intracellular calcium increase
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
Thermo Fisher ScientificThermo Fisher Scientific MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146 Monoclonal Antibody (C146/634)900,300원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146 Monoclonal Antibody (MCAM, 1101)441,900원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146 Monoclonal Antibody (MCAM, 1101)825,100원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146 Monoclonal Antibody (MCAM, 1101)825,100원VAT별도
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