Thermo Fisher Scientific CRMP3 Polyclonal Antibody
CRMP3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS buffer(15mM sodium azide)로 구성되어 있으며, 4°C 또는 -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 111–160 of human CRMP-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2 |
| Contains | 15 mM sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2553598 |
Product Specific Information
- Detects endogenous CRMP3 protein at approximately 50 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3), and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin.
CRMPs are expressed in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, CRMP expression is downregulated but maintained in regions with differentiation and plasticity capacity.
CRMP-3 is transiently expressed in the developing spinal cord and selectively in the postnatal cerebellum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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