Thermo Fisher Scientific BAF53A Recombinant Superclonal Antibody (5HCLC)

Applications

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Pig, Rabbit, and Cat.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies, providing the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
These antibodies recognize multiple epitope sites on the target, offering higher detection sensitivity for low-abundance targets. Each lot maintains consistent composition, eliminating biological variability typical of polyclonal production.

Note: Formerly called “Recombinant polyclonal antibody”; now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

BAF53A is an actin-related protein (ARP) that shares significant sequence identity with conventional actins. ARPs possess an actin fold with an ATP-binding cleft and are involved in cellular processes such as vesicular transport, spindle orientation, nuclear migration, and chromatin remodeling.
BAF53A encodes a 53 kDa subunit of the BAF (BRG1/brm-associated factor) complex in mammals, functionally related to the SWI/SNF complex. It aids transcriptional activation by counteracting chromatin-mediated repression and is required, along with beta-actin, for maximal ATPase activity of BRG1 and chromatin association of the BAF complex.
Three transcript variants encoding two different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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