Thermo Fisher Scientific NME1 Recombinant Superclonal Antibody (11HCLC)

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Rat, Pig, and Bovine.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple recombinant monoclonal antibodies, providing:

• Sensitivity of polyclonal antibodies
• Specificity of monoclonal antibodies
• Consistency of recombinant production

These antibodies recognize multiple epitope sites on the target, enabling higher detection sensitivity for low abundance targets. Each lot has a known mixture of light and heavy chains, eliminating biological variability typical of polyclonal antibody production.

Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. Product and performance remain unchanged.

Target Information

NME1 was identified due to reduced mRNA levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by NME1) and B (encoded by NME2) isoforms.
Mutations in NME1 are found in aggressive neuroblastomas. Two transcript variants encode different isoforms, and co-transcription with NME2 generates fusion proteins sharing sequence identity with both gene products.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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