Thermo Fisher Scientific Phospho-PKC beta-1 (Thr642) Recombinant Superclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Dog, Bovine, and Rabbit.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
Each lot contains a defined mixture of recombinant monoclonal antibodies, ensuring reproducibility and eliminating biological variability.

Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

The PKC family of serine/threonine kinases, including PRKCB1 (PKC beta I), is activated by intracellular signal transduction pathways. In humans, at least 12 PKC isoforms have been identified, differing in structure, localization, and substrate specificity.

PKC alpha, beta I, beta II, and gamma form the conventional family, which are Ca²⁺- and phospholipid-dependent. PKC family members phosphorylate diverse protein targets and play key roles in cellular signaling, acting as major receptors for phorbol esters.

PKC beta I is implicated in B cell activation, apoptosis, endothelial proliferation, and intestinal sugar absorption. In mice, it may regulate neuronal functions and stress-related behaviors. Alternative splicing produces distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.