Thermo Fisher Scientific Apelin Receptor Recombinant Rabbit Monoclonal Antibody (5H5L9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

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Immunohistochemistry (IHC)

-

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Immunocytochemistry (ICC/IF)

2 µg/mL

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Product Specifications

Species Reactivity

Human, Mouse

Published species

Rat

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Monoclonal

Type

Antibody

Clone

5H5L9

Immunogen

Peptides corresponding to Human APLNR (aa 6-20, 52-66) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Apelin Receptor,uniProtId:P35414-1,ncbiNodeId:9606,antigenRange:6-20|52-66,antigenLength:380,antigenImageFileName:702069_Apelin_Receptor_P35414-1_Rabbit.svg,antigenImageFileNamePDP:702069_Apelin_Receptor_P35414-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2633058

Product Specific Information

This antibody is predicted to react with Monkey, Rabbit, Horse and Dog

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

APLNR (Apelin Receptor) is a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.