Thermo Fisher Scientific Apelin Receptor Recombinant Rabbit Monoclonal Antibody (5H5L9)
Apelin 수용체를 인식하는 재조합 토끼 단클론 항체로, WB, IHC, ICC/IF에 사용 가능. 높은 특이성과 재현성을 제공하며, 인간 및 생쥐 반응성. 단백질 A 정제 및 안정한 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5H5L9 |
| Immunogen | Peptides corresponding to Human APLNR (aa 6–20, 52–66) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633058 |
Product Specific Information
This antibody is predicted to react with Monkey, Rabbit, Horse, and Dog.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The DNA sequences encoding the antibody are cloned from immunoreactive rabbits, and individual clones are screened to select the best candidates.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
APLNR (Apelin Receptor) is a member of the G protein-coupled receptor family. It is related to the angiotensin receptor and functions as an apelin receptor that inhibits adenylate cyclase activity.
It plays roles in:
- Cardiovascular and central nervous systems
- Glucose metabolism
- Embryonic and tumor angiogenesis
- Acting as a co-receptor for HIV-1
Two transcript variants resulting from alternative splicing have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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