Thermo Fisher Scientific SERPINA3 Recombinant Rabbit Monoclonal Antibody (11H4L15)
인간 SERPINA3 단백질을 인식하는 재조합 토끼 단클론 항체로, 높은 특이성과 민감도를 제공. ICC/IF에 최적화된 2 µg/mL 농도 사용. 단백질 A 정제 및 동물 유래 성분 없음. 장기 보관 시 -20°C에서 안정적 유지.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 11H4L15 |
| Immunogen | Protein corresponding to human SERPINA3 (aa181–310) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662338 |
Product Specific Information
This antibody is predicted to react with Monkey, Dog, and Cow.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase.
Alpha-1-ACT is a serine protease inhibitor associated with amyloid plaques in Alzheimer’s disease and aged brain tissues. Regulation of serine proteases and their inhibitors is crucial for neuromuscular differentiation.
Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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