Thermo Fisher Scientific AGR2/AGR3 Monoclonal Antibody (AGR3.4)
AGR2/AGR3 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, 인간 시료에 반응하며 WB, IHC, ICC/IF에 사용 가능. 암 발생 마커 연구에 적합하며, 4°C에서 보관. Protein A로 정제된 고순도 항체.
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Thermo Fisher Scientific AGR2/AGR3 Monoclonal Antibody (AGR3.4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AGR3.4 |
| Immunogen | Purified human AGR3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153589 |
Product Specific Information
This antibody recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19–20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
Target Information
AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumors. AGR2 is also reported as a marker of other carcinomas. The Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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