Thermo Fisher Scientific NDUFA13 Polyclonal Antibody
NDUFA13 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 IHC(Paraffin)에 적합하며, 인간 시료에 반응. GRIM-19 관련 연구용으로 사용. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Western Blot (WB): 1:100–1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a portion of human GRIM-19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | PBS/whole serum with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2282593 |
Product Specific Information
Suggested positive control: antigen standard for NDUFA13 (transient overexpression lysate), HeLa whole cell extract.
Target Information
A novel gene associated with Retinoid-IFN-induced Mortality (GRIM), GRIM-19, was identified. Antisense expression of GRIM-19 confers strong resistance against IFN/RA-induced death by reducing intracellular GRIM-19 protein levels. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These findings indicate that GRIM-19 is a novel cell death-regulatory molecule.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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