Thermo Fisher Scientific IKK gamma Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues R(385) R S P P E E P P D F C C P K(399) of human IKK gamma. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IKK gamma,uniProtId:Q9Y6K9-1,ncbiNodeId:9606,antigenRange:385-399|386-399,antigenLength:419,antigenImageFileName:PA1-4162_IKK_gamma_Q9Y6K9-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4162_IKK_gamma_Q9Y6K9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_559596

Product Specific Information

PA1-4162 detects IKK gamma in human samples. This antibody recognizes both human IKK gamma isoforms.

PA1-4162 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~50 kDa protein representing the IKK gamma protein in Interleukin-1-stimulated 293 cells.

The PA1-4162 immunogen is a synthetic peptide corresponding to residues R(385) R S P P E E P P D F C C P K(399) of human IKK gamma.

Target Information

IKK gamma is the regulatory subunit of the inhibitor of the kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.