Thermo Fisher Scientific CD4 Monoclonal Antibody (MEM-241), PE
인간 CD4 항원에 특이적인 Mouse IgG1 단클론 항체로, PE 형광체가 결합되어 있습니다. Flow Cytometry에 최적화되어 있으며, 565/576 nm의 Excitation/Emission 특성을 가집니다. PBS 기반 용액 형태로 제공되며, 4°C에서 암소 보관합니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 20 µL per 100 µL whole blood or 10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-241 |
| Immunogen | 2 N-terminal domains of human CD4 fused to human IgG1 Fc |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1072322 |
Additional Formats
- Unconjugated (MA1-19305)
- APC (MA1-19470)
- Biotin (MA1-19521)
- FITC (MA1-19603)
- PerCP (MA1-19775)
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes an extracellular epitope of CD4 antigen, a 55 kDa transmembrane glycoprotein expressed on a subset of T lymphocytes (“helper” T-cells) and also on monocytes, tissue macrophages, and granulocytes.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but also found in monocytes, macrophages, and dendritic cells. Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and some regions of the brain and gut. CD4 contributes to early T-cell activation via interaction with Lck kinase and may mediate neuronal damage in infectious or immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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