Thermo Fisher Scientific CD36 Monoclonal Antibody (TR9)

Applications and Tested Dilution

Product Specifications

Available Conjugated Formats

• APC
• FITC
• PE
• Request custom conjugation

Product Specific Information

This antibody reacts with an extracellular epitope of CD36 (GPIIIb), an 85 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells, and megakaryocytes.
The TR9 clone cross-blocks binding of FITC-labeled standard antibody OKM5.
Anti-CD36 antibodies inhibit adhesive functions, such as adherence of infected erythrocytes to target cells.

Target Information

CD36, also known as scavenger receptor class B member 3, is a membrane protein expressed on macrophages, platelets, and adipocytes.
It plays a key role in lipid metabolism, inflammation, and atherosclerosis, and mediates recognition and uptake of oxidized LDL, long-chain fatty acids, and apoptotic cells.
CD36 also serves as a receptor for thrombospondin and contributes to cytoadherence of Plasmodium falciparum-infected erythrocytes.
Mutations in CD36 cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.