Thermo Fisher Scientific CD186 (CXCR6) Monoclonal Antibody (DANID2), PE, eBioscience

Thermo Fisher Scientific CD186 (CXCR6) Monoclonal Antibody (DANID2), PE, eBioscience

Applications and Tested Dilution

• Application: Flow Cytometry (Flow)
• Tested Dilution: 1 µg/test

Product Specifications

Product Specific Information

This DANID2 monoclonal antibody recognizes mouse CD186 (CXCR6). It is suitable for flow cytometry on both native and paraformaldehyde-fixed cells.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Mouse splenocytes, ≤1.0 µg per test (100 µL final volume). Cell number may range from 10⁵–10⁸ cells/test.
• Recommended: Titrate for optimal performance.
• Excitation: 488–561 nm
• Emission: 578 nm
• Laser Compatibility: Blue, Green, Yellow-Green lasers

Target Information

CD186 (CXCR6) is a G protein-coupled chemokine receptor known as a cellular receptor for HIV and SIV. It is expressed on NKT cells, activated and memory T cell subsets, and some plasma cells. In mice, liver NK cells express CD186, unlike naïve or splenic NK cells. Its ligand, CXCL16, is expressed by macrophages, dendritic cells, and liver endothelial cells. CD186 serves as a marker for NKT cell identification.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Additional Formats

• APC
• PerCP-eFluor 710
• Custom conjugation available upon request

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