Thermo Fisher Scientific PCBP4 Polyclonal Antibody
Thermo Fisher Scientific의 PCBP4 Polyclonal Antibody는 인간 PCBP4 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 sodium azide를 포함한 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide from near the carboxy terminus of human MCG10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Refrigerate at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153622 |
Product Specific Information
- Suggested positive control: HeLa cell lysate
- PA5-20359 can be used with blocking peptide PEP-0479.
Target Information
MCG10 is a member of the KH-domain RNA-binding protein family, also known as alpha-CPs, which bind RNA with specificity for C-rich pyrimidine regions. These proteins play important roles in post-transcriptional regulation and exhibit different cellular distributions.
MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Overexpression in transfected cells suppresses cell proliferation by inducing apoptosis and cell cycle arrest in G2-M.
Decreased expression of one isoform of MCG10 has been observed in many lung cancers, suggesting a potential tumor suppressor role. Multiple alternatively spliced isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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