Thermo Fisher Scientific CD82 Polyclonal Antibody
CD82 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 냉장 또는 -20°C 장기 보관 가능.
- 카탈로그번호
- PA520356
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the carboxy terminus of human KAI1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Refrigerate at 2–8°C for up to 3 months; for long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155621 |
Product Specific Information
A suggested positive control is A549 cell lysate.
PA5-20356 can be used with blocking peptide PEP-0476.
Target Information
CD82 (KAI1) is a metastasis suppressor gene product and a membrane glycoprotein belonging to the transmembrane 4 superfamily. Expression of this gene is downregulated during tumor progression and can be activated by p53 through a consensus binding sequence in its promoter. Expression levels of CD82 and p53 are strongly correlated, and loss of both is associated with poor survival in prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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