Thermo Fisher Scientific Phospho-IFNGR1 (Tyr457) Polyclonal Antibody
Phospho-IFNGR1 (Tyr457) 항체로, 인산화된 IFNGR1 단백질을 특이적으로 검출 가능. Western blot 및 IHC(Paraffin) 적용 가능. Rabbit Polyclonal 형식으로 높은 특이성과 재현성 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IFNGR1 (Accession P15260), corresponding to amino acid residues around phosphorylated Tyr457 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816931 |
Product Specific Information
Antibody detects endogenous levels of IFNGR1 only when phosphorylated at Tyr457.
Target Information
The IFNGR1 gene encodes the ligand-binding chain (alpha) of the gamma interferon receptor. The human interferon-gamma receptor is a heterodimer composed of IFNGR1 and IFNGR2. Genetic variations in IFNGR1 are associated with susceptibility to Helicobacter pylori infection, and defects in IFNGR1 can cause Mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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