Thermo Fisher Scientific Phospho-IFNGR1 (Tyr457) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human IFNGR1(Accession P15260), corresponding to amino acid residues around phosphorylated Tyr457. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IFNGR1 (CD119),uniProtId:P15260-1,ncbiNodeId:9606,antigenRange:457,antigenLength:489,antigenImageFileName:PA5-105503_IFNGR1_CD119_P15260-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105503_IFNGR1_CD119_P15260-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816931

Product Specific Information

Antibody detects endogenous levels of IFNGR1 only when phosphorylated at Tyr457.

Target Information

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.