Thermo Fisher Scientific ARHGEF10 Polyclonal Antibody
ARHGEF10 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 IHC(P) 검증 완료. 고순도(>95%) 항체로 신경형태 형성과 관련된 연구에 적합합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in human ARHGEF10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553818 |
Product Specific Information
This antibody detects endogenous ARHGEF10 protein at a molecular weight of approximately 152 kDa.
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
The ARHGEF10 gene encodes a Rho guanine nucleotide exchange factor (GEF).
Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of GDP for GTP and may play a role in neural morphogenesis.
Mutations in this gene are associated with slowed nerve conduction velocity (SNCV).
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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