Thermo Fisher Scientific PAX8 Monoclonal Antibody (PAX8, 1491)
PAX8 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot 및 IHC 등 다양한 응용에 적합. 인간 종에 반응하며, Protein A/G로 정제된 액상 형태. 4°C에서 보관하며 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PAX8, 1491 |
| Immunogen | Recombinant fragment (around aa 60–261) of human PAX8 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
This gene encodes a member of the paired box family of transcription factors. Members of this family typically encode proteins containing a paired box domain, an octapeptide, and a paired-type homeodomain.
This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes.
Mutations in this gene are associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical follicular thyroid adenomas.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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