Thermo Fisher Scientific PAX8 Monoclonal Antibody (PAX8, 1491)
PAX8 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot 및 IHC(Paraffin) 등 다양한 응용에 적합. Recombinant human PAX8(aa 60-261)을 면역원으로 사용. 단백질 A/G 정제, PBS 버퍼에 보존, 무보존제. 연구용으로만 사용 가능.
- 카탈로그번호
- 7849-MSM1-P1ABX
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PAX8, 1491 |
| Immunogen | Recombinant fragment (around aa 60–261) of human PAX8 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
This gene encodes a member of the paired box family of transcription factors. Members of this family typically encode proteins containing a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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