Thermo Fisher Scientific PAX8 (Renal Cell Marker) Monoclonal Antibody (PAX8/1492)
PAX8 단백질을 인식하는 단클론 항체로, 신장 세포 마커 분석에 적합합니다. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 사용 가능하며, 인간 및 개 시료에 반응합니다. 단백질 A/G 정제, PBS 용액 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PAX8/1492 |
| Immunogen | Recombinant fragment (around aa 60–261) of human PAX8 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the paired box (PAX) family of transcription factors. These proteins typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. PAX8 is a nuclear protein involved in thyroid follicular cell development and regulation of thyroid-specific gene expression. Mutations in this gene are associated with thyroid dysgenesis, follicular carcinomas, and atypical follicular adenomas. Several alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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