Thermo Fisher Scientific PAX8 Monoclonal Antibody (PAX8, 1491)
PAX8 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot, IHC, Peptide Array 등 다양한 응용에 적합합니다. 인간 PAX8 단백질(aa 60-261) 재조합 절편으로 면역화되었으며, 고순도 Protein A/G 정제 및 안정적 PBS 버퍼로 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PAX8, 1491 |
| Immunogen | Recombinant fragment (around aa 60–261) of human PAX8 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature (RT).
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at RT for 20 min.
Target Information
This gene encodes a member of the paired box family of transcription factors. Members of this family typically encode proteins containing a paired box domain, an octapeptide, and a paired-type homeodomain.
This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes.
Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical follicular thyroid adenomas.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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