Thermo Fisher Scientific RANBP1 Recombinant Rabbit Monoclonal Antibody (HL2358)
RANBP1 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체(HL2358). WB, IHC, ICC/IF 등 다양한 응용에 적합하며, 인간·마우스·랫트 반응성. 고순도 Protein A 정제, 1 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2358 |
| Immunogen | Recombinant fragment of human RanBP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093816 |
Target Information
Ran/TC4-binding protein (RanBP1) interacts specifically with GTP-charged RAN. The RANBP1 gene encodes a 23-kDa protein that binds RAN complexed with GTP but not GDP. It does not activate GTPase activity of RAN but increases GTP hydrolysis by RanGAP1. The RANBP1 cDNA encodes a 201-amino acid protein with 92% similarity to its mouse homolog. In both mammalian cells and yeast, RanBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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