Thermo Fisher Scientific SLC7A5 Recombinant Rabbit Monoclonal Antibody (HL2353)
SLC7A5 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot, IHC, ICC/IF 등에 사용 가능. 인간, 마우스, 랫트에 반응하며, Protein A 정제 및 PBS 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2353 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human LAT1/SLC7A5. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3094275 |
Target Information
Solute carrier family 7 member 5 (SLC7A5), also known as large neutral amino acids transporter small subunit 1 (LAT1), is a sodium-independent, high-affinity transporter of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine, and tryptophan when associated with SLC3A2/4F2hc.
It is involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, as well as thyroid hormones triiodothyronine (T3) and thyroxine (T4) across cell membranes in tissues such as placenta.
Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in the brain.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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