Thermo Fisher Scientific HEY1 Recombinant Rabbit Monoclonal Antibody (HL2367)
HEY1 단백질을 인식하는 Recombinant Rabbit Monoclonal 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, Protein A로 정제된 고순도 항체입니다. 연구용으로 Notch 신호전달 관련 단백질 분석에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:10000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2367 |
| Immunogen | Recombinant fragment of human HEY1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093840 |
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch signaling pathway protein.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain.
HEY1 acts as a downstream effector of Notch signaling and may be required for cardiovascular development.
It functions as a transcriptional repressor binding preferentially to the canonical E-box sequence (5'-CACGTG-3') and represses transcription by cardiac transcriptional activators GATA4 and GATA6.
HEY1 is also reported to be expressed during development of the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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