
Thermo Fisher Scientific HNF4A Polyclonal Antibody, MaxPab
HNF4A 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 in situ PLA에 적합합니다. 인간과 생쥐 반응성을 가지며 PBS buffer에 보관됩니다. 간, 신장, 장, 췌장 등에서 발현되는 HNF4A 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
in situ PLA (PLA)
- Tested Dilution: 1:1200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HNF4A (NP_849180.1, 1 a.a. ~ 464 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA PNSLGVSALC AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSRQITSPVS GINGDIRAKK IASIADVCES MKEQLLVLVE WAKYIPAFCE LPLDDQVALL RAHAGEHLLL GATKRSMVFK DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYAYLK AIIFFDPDAK GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL FGMAKIDNLL QEMLLGGSPS DAPHAHHPLH PHLMQEHMGT NVIVANTMPT HLSNGQMSTP ETPQPSPPGG SGSEPYKLLP GAVATIVKPL SAIPQPTITK QEVI
Target Information
Hepatocyte nuclear factor 4 alpha (HNF4α) is an orphan nuclear receptor expressed in the liver, kidney, intestine, and pancreas.
Mutation of HNF4α in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1).
HNF4 binds to DNA as an exclusive homodimer.
The HNF4α gene is alternatively spliced and may generate up to nine different isoforms (HNF4α1 through HNF4α9).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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