Thermo Fisher Scientific CXCR2 Polyclonal Antibody
CXCR2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합합니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. IL-8 수용체 연구 및 신호전달 관련 연구에 활용 가능합니다.
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- PA533455
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from N-terminal extracellular domain of human CXCR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550835 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla (100%), Monkey (88%)
Target Information
CXCR2 is a receptor for interleukin-8 (IL-8), a powerful neutrophil chemotactic factor and a member of the GPCR family.
Binding of IL-8 to CXCR2 activates neutrophils through a G-protein-mediated phosphatidylinositol-calcium second messenger system.
CXCR2 binds IL-8, GRO/MGSA, and NAP-2 with high affinity and is expressed in a wide variety of tissues.
ESTs have been isolated from human placenta and thymus libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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