Thermo Fisher Scientific TRPA1 Polyclonal Antibody, DyLight 488
TRPA1 단백질을 인식하는 DyLight 488 형광 표지 폴리클로날 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 사용 가능. Rabbit IgG 기반으로 항원 친화 크로마토그래피로 정제됨. 인간, 생쥐, 랫드, 기니피그, 제브라피쉬 반응성.
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Thermo Fisher Scientific TRPA1 Polyclonal Antibody, DyLight 488
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:250 |
| Immunohistochemistry (Frozen) (IHC-F) | 0.5–1.0 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (N-terminus residues 1–100) of human TRPA1 protein |
| Conjugate | DyLight™ 488 |
| Excitation / Emission Max | 492 / 519 nm |
| Form | Liquid |
| Concentration | 0.67 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 50 mM sodium borate |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153919 |
Product Specific Information
- Target sequence has 69% sequence homology with rat.
- Suggested positive control: human brain membrane fraction.
Target Information
TRPA1 is a TRP-related channel responsive to cold temperatures and pungent compounds, involved in nociceptor and hair cell transduction. It is expressed mainly in sensory neurons and lung epithelia and may serve as a therapeutic target for cold hyperalgesia. TRPA1 is also expressed outside the CNS and is dysregulated during oncogenic transformation. Structurally related to ankyrin and transmembrane proteins, TRPA1 may play roles in signal transduction and growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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