Thermo Fisher Scientific Vimentin (Mesenchymal Cell Marker) Recombinant Rabbit Monoclonal Antibody (VIM/6576R)
중간엽 세포 마커인 Vimentin을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot 및 면역조직화학 실험에 적합하며, 다양한 종에 반응합니다. HEK293 세포 발현, Protein A/G 정제, 보존제 무첨가 PBS 용액 형태로 제공됩니다.
- 카탈로그번호
- 7431RBM13P1ABX
- 판매단위
- pk
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Thermo Fisher Scientific Vimentin (Mesenchymal Cell Marker) Recombinant Rabbit Monoclonal Antibody (VIM/6576R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Chicken, Horse, Cat, Human, Pig, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | VIM/6576R |
| Immunogen | Recombinant full-length human Vimentin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
- Does not react with Mouse
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular transport of proteins between the nucleus and plasma membrane. Vimentin is co-expressed with desmin during early cellular development and later replaced by tissue-specific IFPs.
It plays a role in steroid synthesis by serving as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin leads to filament breakdown and cytoskeletal changes that facilitate lipid droplet interaction with mitochondria, enhancing steroidogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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