Thermo Fisher Scientific Vimentin (Mesenchymal Cell Marker) Recombinant Rabbit Monoclonal Antibody (VIM/1937R)
Mesenchymal cell marker로 사용되는 Vimentin에 특이적인 recombinant rabbit monoclonal antibody. 다양한 종에 반응하며 WB, IHC, ICC, Flow 등 다중 응용 가능. HEK293 발현, Protein A/G 정제, 4°C 보관.
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Thermo Fisher Scientific Vimentin (Mesenchymal Cell Marker) Recombinant Rabbit Monoclonal Antibody (VIM/1937R)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Chicken, Horse, Cat, Human, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | VIM/1937R |
| Immunogen | Recombinant full-length human Vimentin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Mouse
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular transport of proteins between the nucleus and plasma membrane. Vimentin is expressed along with desmin during early cellular development, later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by serving as a storage network for cholesterol-containing lipid droplets. Vimentin phosphorylation by protein kinase leads to cytoskeletal reorganization facilitating cholesterol transport to mitochondria, enhancing steroid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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