Thermo Fisher Scientific SPG7 Monoclonal Antibody (OTI2B9), TrueMAB
SPG7 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot 및 Immunocytochemistry에 적합. Human 시료에 반응하며, Lyophilized 형태로 제공. 고순도의 Affinity Chromatography 정제 및 안정적 PBS buffer 보존.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 300–573 of human SPG7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The SPG7 gene encodes a mitochondrial metalloprotease protein belonging to the AAA family. Proteins in this family share an ATPase domain and are involved in various cellular processes such as membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis.
Mutations in this gene are associated with autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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