Thermo Fisher Scientific SPG7 Monoclonal Antibody (OTI1D10), TrueMAB
SPG7 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 휴먼 SPG7 재조합 단백질(aa 300–573)을 면역원으로 제작되었으며, Lyophilized 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 300–573 of human SPG7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SPG7 encodes a mitochondrial metalloprotease belonging to the AAA protein family. These proteins contain an ATPase domain and are involved in membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis.
Mutations in SPG7 cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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