Thermo Fisher Scientific NMBR Polyclonal Antibody
Rabbit polyclonal antibody targeting human NMBR C-terminus. Validated for Western blot (1:500–1:3,000). Recognizes multiple species including mouse and rat. Supplied as 1 mg/mL liquid, unconjugated. Store at 4°C short term or -20°C long term.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of Human NMBR (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2736234 |
Product Specific Information
- Positive Control: HeLa, HeLa (500 µM CoCl₂ treatment for 24 hr)
- Predicted Reactivity: Mouse (88%), Rat (88%), Pig (85%), Rhesus Monkey (96%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
NMBR (Neuromedin B Receptor)
NMBR is a Bombesin receptor that activates phospholipase and protein kinase C, enhancing calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and gastrointestinal epithelial tissues. Expression has been reported in brain (olfactory bulb, thalamus), colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. It is also present in cancers of the lung, ovary, and prostate. ESTs have been isolated from B-cell, lung, testis, and brain libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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