Thermo Fisher Scientific NMBR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of Human NMBR. The exact sequence is proprietary. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NMBR,uniProtId:P28336-1,ncbiNodeId:9606,antigenRange:390,antigenLength:390,antigenImageFileName:PA5-78080_NMBR_P28336-1_Rabbit.svg,antigenImageFileNamePDP:PA5-78080_NMBR_P28336-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2736234

Product Specific Information

Positive Control: HeLa, HeLa (500 µM CoCl2 treatment for 24 hr)

Predicted Reactivity: Mouse (88%), Rat (88%), Pig (85%), Rhesus Monkey (96%), Bovine (93%)

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.