Thermo Fisher Scientific CD5 Monoclonal Antibody (FE1.1B11), PE

Applications

• Flow Cytometry (Flow): Neat–1:10 dilution tested

Product Specifications

Additional Formats

• FITC
• Request custom conjugation

Product Specific Information

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark.
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.

Target Information

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation.
CD5 is found on approximately 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, reactivity is mainly observed in T-cell areas. CD5 expression is associated with many T-cell leukemias, lymphomas, and activated T cells.
Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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