Thermo Fisher Scientific Calcitonin Monoclonal Antibody (4-5)

Applications

Tested Dilution

Publications

ELISA (ELISA)

20 µg/mL

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

4-5

Immunogen

Salmon calcitonin.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_889467

Product Specific Information

MA3-021A detects calcitonin (CT) from salmon tissues. This antibody cross reacts with glycine-extended salmon calcitonin, but is unreactive with salmon calcitonin peptides 23-30 and 26-32. It shows no cross reactivity with human calcitonin.

MA3-021A has been successfully used in ELISA procedures. By ELISA this antibody is useful in solid-phase or competitive solution based procedures with a sensitivity of approximately 50 ng/mL.

The MA3-021A antigen is salmon calcitonin. This antibody was raised against salmon calcitonin which, as in the naturally occurring peptide, contains a C-terminal prolinamide. The epitope recognized likely lies in the N-terminal portion of the molecule.

Reconstitute with PBS.

Target Information

Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.