Thermo Fisher Scientific ALX4 Monoclonal Antibody (OTI1F2), TrueMAB
ALX4 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 IHC(P) 적용 가능. HEK293T 세포에서 발현된 full-length human ALX4 단백질로 면역화. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F2 |
| Immunogen | Full-length human recombinant protein of human ALX4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue.
Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones.
Mutations also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role in craniofacial development, mesenchymal-epithelial communication, and hair follicle development.
Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), which features craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males.
In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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