Thermo Fisher Scientific Factor VII Monoclonal Antibody (RFF-VII/2)
인간 Factor VII에 특이적인 단클론 항체로 혈액 응고 연구에 사용됩니다. Western blot, IHC, ELISA, RIA 등 다양한 응용 가능. 단백질 G로 정제된 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (IHC)
- Assay-dependent
- View 1 publication
ELISA
- Assay-dependent
Radioimmune Assays (RIA)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RFF-VII/2 |
| Immunogen | Purified Factor VII |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538409 |
Product Specific Information
This antibody binds to a conformational epitope and will not bind to reduced Factor VII.
Mouse anti-Human Factor VII antibody, clone RFF-VII/2 recognizes Factor VII, a serine protease found circulating in the blood. It initiates the extrinsic pathway of blood coagulation in conjunction with tissue factor.
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form and is converted to an active form by factor IXa, factor Xa, factor XIIa, or thrombin through minor proteolysis. Upon activation, a heavy chain containing a catalytic domain and a light chain containing two EGF-like domains are generated and held together by a disulfide bond. In the presence of factor III and calcium ions, activated factor VII further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa.
Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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