Thermo Fisher Scientific PTGDS Polyclonal Antibody
PTGDS 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 종에 반응하며 Western blot에 검증됨. 고순도 항원 친화 크로마토그래피로 정제, 액상 형태로 제공. 신경 및 생식계 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 2 µg/mL
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Cat, Human, Mouse, Non-human primate, Rabbit, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to a region within residues 120–190 of the human PTGDS protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 30% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2174501 |
Product Specific Information
This antibody has 89% sequence homology with equine, 85% with sheep, and 82% with porcine samples.
Suggested positive control: antigen standard for PTGDS (transient overexpression lysate), human brain protein.
Target Information
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2).
PGD2 functions as a neuromodulator and trophic factor in the central nervous system. It is also involved in smooth muscle contraction/relaxation and inhibits platelet aggregation.
PTGDS contributes to the maintenance of various biological barriers (blood-brain, blood-retina, blood-aqueous humor, blood-testis) and may regulate non-rapid eye movement (NREM) sleep.
It is abundant in cerebrospinal fluid and may act as a Beta-Amyloid chaperone implicated in Alzheimer’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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