Thermo Fisher Scientific PTGDS Polyclonal Antibody
Rabbit polyclonal antibody targeting human PTGDS protein. Validated for Western blot with broad species reactivity. High purity via antigen affinity chromatography. Supplied as liquid form with PBS and glycerol buffer. Ideal for CNS and prostaglandin p...
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Applications
- Western Blot (WB): Tested dilution 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Horse, Cat, Fish, Human, Mouse, Non-human primate, Pig, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within residues 25–100 of human PTGDS protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 30% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2174502 |
Product Specific Information
This antibody shows 87% sequence homology with ovine and 82% with rabbit.
Suggested positive control: antigen standard for PTGDS (transient overexpression lysate), human brain protein.
Target Information
PTGDS encodes a glutathione-independent prostaglandin D synthase that catalyzes the conversion of PGH2 to PGD2.
PGD2 acts as a neuromodulator and trophic factor in the central nervous system, influences smooth muscle contraction and platelet aggregation, and contributes to the integrity of blood-brain and related barriers.
PTGDS is abundant in cerebrospinal fluid and may function as a β-amyloid chaperone, potentially involved in Alzheimer’s disease pathology.
Research indicates roles in CNS maturation, maintenance, and regulation of non-rapid eye movement (NREM) sleep.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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