Thermo Fisher Scientific RAB3c Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues M(9) A S A Q D A R F G Q K D S S D Q N(26) C of rat RAB3C. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAB3c,uniProtId:P62824-1,ncbiNodeId:10114,antigenRange:9-26,antigenLength:227,antigenImageFileName:PA1-772_RAB3c_P62824-1_Rabbit.svg,antigenImageFileNamePDP:PA1-772_RAB3c_P62824-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2177220

Product Specific Information

PA1-772 detects rab 3C from mouse and rat tissues and cells.

PA1-772 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects a 22 kDa protein representing rab 3C from AtT20 cell extract.

PA1-772 immunogen is a synthetic peptide corresponding to residues M(9) A S A Q D A R F G Q K D S S D Q N(26) C of rat RAB3C. This immunizing peptide (Cat. # PEP-106) is available for use in neutralization and control experiments.

Target Information

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland, and pituitary.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.