Thermo Fisher Scientific CSP alpha Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2-4 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues E(180) T T Q L T A D S H P S Y H T D G F N(198) of rat CSP. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CSP alpha,uniProtId:P60905-1,ncbiNodeId:10114,antigenRange:181-198,antigenLength:198,antigenImageFileName:PA1-776_CSP_alpha_P60905-1_Rabbit.svg,antigenImageFileNamePDP:PA1-776_CSP_alpha_P60905-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2095043

Product Specific Information

PA1-776 detects Cysteine String Protein Alpha in mouse and rat brain samples.

PA1-776 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~34 kDa protein representing Cysteine String Protein Alpha in rat and mouse brain homogenates.

The PA1-776 immunogen is a synthetic peptide corresponding to residues E(180) T T Q L T A D S H P S Y H T D G F N(198) of rat CSP. This sequence is conserved across many species including mouse, human and bovine. This peptide (Cat. # PEP-287) is available for use in neutralization and control experiments.

Target Information

Cysteine string protein alpha (CSPalpha) is a synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40 chaperones. Cysteine-string proteins are membrane-bound proteins associated primarily with nerve endings and synaptic vesicles in the brain. These proteins play an important role in presynaptic function and may be involved in calcium-dependent neurotransmitter release. CSP proteins may act as presynaptic chaperones that assist in maintaining synaptic function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.